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A material scientist, a biologist, a physicist, and a boat driver are in dingy in the middle of a river with a crocodile in a cage.
The boat driver is nervous and is worried the crocodile might brake out of the cage and eat them all.  

The material scientist says he doesn’t need to worry about the crocodile breaking out because the cage is much to strong for the crocodile to break out.
The biologist says he doesn’t need to worry about the crocodile breaking out because the crocodile was recently fed and won’t attempt to break out until it is hungry.
The physicist says that he doesn’t need to worry about the crocodile breaking out because with four people, a crocodile and a heavy metal cage in the dingy the boat will soon sink and they will all drown.

👩‍🏫👩‍🔬👨‍🏫🚤🐊 

🚤🐊💢

👩‍🏫Cage👍

👩‍🔬Fed

👨‍🏫🚤💢🚤💢

A material scientist, a biologist, a physicist, and a boat driver are in dingy

   in the middle of a river with a crocodile in an cage.

A boat drive is nervous and is worried the crocodile might break out of the cage and eat them all.

The material scientist says he doesn't need to worry about the crocodile breaking out

    because the cage is much too strong for the crocodile to break out.

The biologist say he doesn't need to worry about the crocodiel breaking out

    because the crocodile was recently fed and won't attempt to break out until it is hungry.

The physicist says he doesn't need to worry about the crocodile breaking out

    with four people, a corocodile and heavy metal cage in the dingy 

    the boat will soon sink and they will all drown.

Scientist gag는 어이없어서 웃김 ㅋ

Two women were fighting for the last available seat on the bus.
No amount of reasoning was helping the bus driver resolve the issue. 

In desperation, he grabbed his training manual and announced:

'The policy is to allow the seat to go to the uglier one.'

Both women stood for the remainder of the trip.

👩💢👩‍🦳 버스 자리 놓고 싸움

🚌 버스 기사가 해결 못함

📒 매뉴얼을 들고

👿 못난이한테 자리 준다

🧍‍♀️🧍‍♀️ 둘다 서서 감

Two women were fighting for the last available seat on the bus.

No amount of reseaning was helping the bus dirver resolve the issue.

In desperation, he grabbed his traing manual and annouced:

'The policy is to allow the seat to go to the uglier one.'

Both women stood for the remainder of the trip.

"어린이집 가기 싫어!"

"왜 어린이집에 안가?"

"아빠가 싫어서!"

"어..."

대화에서 이유를 묻는 것은 상대를 이해하지 못한 행동이다.

새해 다섯살이 된 딸아이는 당당하게 이야기 한다.

"나 오늘 어린이집 가기 싫어!"

친구와 싸웠나, 선생님께 혼났나 하는 지레짐작은 아이에게 질문하게 만든다.

그리고 아이는 깨끗하게 걱정을 지운다.

"아빠가 싫어서!"

여기서 "아빠가 왜 싫어?" 묻는 것은 그날 아침을 블랙홀에 빠뜨리는 짓이다.

그렇다면 그냥 그런 것이다.

오늘 아침 아이의 답변은 나로 새롭게 생각하게 만든다.

그동안 얼마나 많은 무의미한 'WHY'로 대화와 관계에서 스스로 어려움을 만들었던가.

나는 '왜'를 위한 '왜'로 피곤하게 살았다.

상대가 '왜' 저렇게 말했을까? 무슨 의도가 있는 것은 아닐까?

대화에서 이유에 집중하는 바람에 본질을 매번 잊었다.

본질은 '오늘은 어린이집에 갈 맘이 없다'이고, '너가 시킨대로 하기 싫어', '나는 내가 하고 싶은 대로 하고 싶어'이다.

이유는 없다.

애닳고 곤란한 내 관계의 원인은 아이러니하게도 '왜'였다. '

'왜' 없이 대화할 수 있는 어른이가 될 수 있을까?

"어린이집 가기 싫어!"

"음, 아빠도 회사 가기 싫어!"

그렇다면 그런대로 너도 나도 그렇구나.

짧고 쉬운 문단 소스를 Reddit Jokes로 바꿨다.

뉴스는 아직 쉽지 않아서.

스토리텔링이나 구동사, 구어체 익히는데 도움이 되었으면 한다.

그런데 잘 외워지는 것은 왜인데...🤓

👰‍♀️🤵  I received a wedding invitation.

💌      It read, "Your presence itself is a present. We don't want any presents at the wedding."

🎁      After re-reading it repeatedly, I concluded that I was not invited. So I decided not to attend.

🔄      The invitation should have said "The only present we want is the present of your presence."

                                                                                                                                      from Reddit/Jokes

👰‍♀️🤵  청첩장 받음

💌      너가 오는게 선물. 우린 선물 필요 없어~

🎁      다시 읽고, 안가기로 했어!

🔄      니가 오는게 선물이야! (댓글 내용 추가한 것)

I recieved a wedding invitation.

It read, "Your presence itself is a present. We don't want any presents at the wedding."

After re-reading it repeatedly, I concluded that I was not invited. So, I decided not to attend.

The invitation should have said "The only present we want is the present of your presence."

I recieved a wedding invitation.

It read, "Your presence itself is a present. We don't want any present at the wedding."

After re-reading it repeatedly, I concluded that I was not invited. So, I decided not to attend.

The invitation should have said "The only present we want is the present of your presence."

I'm Anna Marie Pyle from Yale University,

and today I'd like to tell you about RNA structure.

And I'm hoping, by the end of this seminar,

that you'll be thinking about RNA as a much more complex molecule

than you might have thought about it before.

One of the things that's important to keep in mind is that,

for any biomolecule, very often one sequence will lead to a unique structure,

and this is true for proteins and it's also true for many RNA molecules.

Today, I hope to tell you how that can be achieved.

Now, some RNA molecules are actually unstructured,

like messenger RNAs (mRNAs) that contain the code for translating your protein.

But other RNA molecules have elaborate structures,

such as tRNA molecules, ribozymes - which are catalytic RNAs,

the ribosome - which is the factory that makes your proteins,

and riboswitches.

I'm showing you a riboswitch in this image here.

RNA molecules are often highly complex in structure

and it's important to remember that

structured RNAs are involved in almost every aspect of gene expression.

I'm showing you some examples here.

In this case, this is one of nature's biosensors:

it's called a riboswitch, and it's important for bacteria

so that they can sense metabolites in their environments

and signal back to the cell.

This is a catalytic RNA called a self-splicing group II intron,

and it's a molecule that can cut and stitch RNA and DNA molecules

so that they can go on to be functional.

And here, this giant RNA is your protein synthesis factory,

which ironically is an RNA molecule and it is probably one of the largest

and most highly structured RNAs in our cells.

But even if you're most interested in the function of messenger RNAs,

it's important to remember that many messenger RNAs also contain highly structured regions.

So even though the middle part of an mRNA molecule often just contains the coding region,

the triplets that encode the amino acids for your proteins,

often the RNA sequences, at their termini,

form these complex structures in the untranslated regions

and these help to regulate the process of protein synthesis.

So the chemical structure of RNA is a big part of how it can achieve these many functions

and how it adopt these complex structures.

And a couple of very important things distinguish RNA from its cousin, the DNA molecule.

So, in addition to the 2' hydroxyl groups that you see here,

the Uracil base looks a lot like Thymidine,

but it's missing the 5-methyl group at this position.

So, one of the bases on RNA is different than it is on DNA.

But, back to the 2' hydroxyl group (2'-OH),

which is really the thing that endows RNA with special capabilities.

I like to say the 2'-OH group gives RNAs "Special Powers",

and the reason for that is that this substituent can both accept and donate a hydrogen bond.

So, every 2'-OH group can make up to two hydrogen bonds.

So, the bottom line is that makes the RNA backbone very sticky

and enables RNAs to make a number of types of interactions

that are impossible if you just have a deoxyribose at this position.

In addition to the chemical structure of RNA,

another thing that gives it its shape and distinguishes it from DNA is the structure of the sugar moiety.

So a lot of times people think that the things that make DNA and RNA molecules special are the sequences of the bases and the base pairings between them.

But a lot is going on with the sugar-phosphate backbone,

and in particular it's important to remember that sugars are not flat.

Because they're five-membered rings,

they often buckle or pucker, and this gives both RNA and DNA their distinctive shapes,

and we'll be talking about those more in a moment.

There are two main conformations of the sugar pucker in a ribose

and one of them is the C3'-endo pucker.

And so if we imagine the sugar is in this position here,

the 3' atom of the sugar pushes up,

I like to say it's pushing in toward the plane of the base,

and this gives you the C3'-endo conformation.

The consequence of that conformation is that the inter-phosphate distance is very small:

it's only 5.9 Angstroms in an RNA-like sugar.

However, these sugars are always flexing,

especially if they're in the absence of surrounding structure,

and an alternative conformation that can be adopted by ribose is the C2'-endo conformation,

which is actually the one that's dominant in DNA.

And that occurs when this carbon kicks it's knee up and,

at the C2' position, becomes closer to the base.

The consequence of that is that the inter-phosphate distance gets very large:

it's 7 Angstroms.

And that's why you'll see, later in the presentation,

that DNA duplexes are more elongated and spread out than RNA duplexes.

It also is an important factor in giving RNA and DNA their helical shape.

Okay, so now that we've covered some of the most important aspects of primary structure in nucleic acids,

let's talk a little bit about the secondary structure.

And some terminology is helpful.

First of all, it's important to define RNA secondary structure as the regions of RNA base pairing.

So, I'm exemplifying this with the secondary structure of tRNA.

But first, let's look at the parts list a bit.

I'm showing you here, a simplified representation of two stems.

And so, if we were to discuss these, you would see that there are two duplex stems in this structure.

One of them is capped by a hairpin loop,

and often these are triloops, with three nucleotides, or tetraloops, with four nucleotides.

And in this case, and in many cases,

stems are joined by substructures that we call junctions.

The base pairs in an RNA secondary structure are the usual suspects: A-U, G-C,

but in RNA alternative base pairings are readily tolerated.

And I'll show you one example, that is the G-U wobble pair.

In G-U pairs, there is a structure that differs slightly from Watson-Crick base pairing.

What we see in a G-U wobble pair is that the line of the bases is slightly different

because they have a different hydrogen bonding arrangement than an A-U pair does, which you can see down here.

You can see that in the G-U wobble pair, the uridine is displaced upward in this representation,

and then that also causes this amine group in the guanosine to project far out into the minor groove of RNA.

So, interestingly, when you have a G-U wobble pair in an RNA duplex,

it has almost no perturbation to the structure

that you can see by eye when you solve the structure.

So, it's readily tolerated and has a similar stability to an A-U pair, in RNA anyway.

There are other kinds of weird base pairings that are tolerated.

At certain pHs, cytosines become protonated and we see A-C wobble pairs.

It's often common to see uridine-uridine pairs and G-A pairs,

although because these involve two purines, that are large bases,

they're typically only seen and stabilized at the ends of duplexes.

So what are some other kinds of RNA secondary structural arrangements?

I've just shown you that you can have duplexes that are terminated by hairpin loops, that connect the strand,

but there are other types of loop structures that have important significance for the overall structure.

There are asymmetric loops, as I've shown you here.

This one has three bases that stick out, and this one has one.

Often times, this kind of arrangement causes a bend in the duplex.

And this is a symmetric set of mismatches and, often times what you observe in a real structure is

that the RNA is not highly perturbed at these positions and that these bases,

which don't like to be out in water, will tuck in and behave as if they were base pairing.

Another thing that is important to point out about representations like the ones

I've just shown you is that, right now, I've shown you loop nucleotides that are sticking out like the spines of a cactus.

It's important to say that this almost never happens

because nucleoside bases are aromatic, like benzene.

They don't like water and they like to stack upon each other.

And so most of the time, they'll make an effort to tuck in to produce specific structures.

So, when I was saying to you before that mismatched bases,

that are asymmetrical within a duplex, have very little perturbation,

I meant that because that's been seen in high-resolution structures, such as shown here.

You probably wouldn't be able to tell that in this structure,

there are two "unpaired" bases.

They've simply stacked in to get out of the aqueous environment.

Anyway, these are some of the perturbations of RNA secondary structure.

So, one of the things I'd like to point out is that the sequences at duplex termini are often highly conserved in sequence.

This sequence here (UUCG) is frequently found within substructures that require extra stabilization

and, interestingly, if you solve the structure of hairpin sequences like this,

this region here will always have the same three-dimensional structure as shown here,

which was one of the original NMR structures that characterized the arrangement of bases in this sequence.

So let's take a close look at the overall topology of RNA secondary structure.

What do RNA helices actually look like?

So we often say that RNA duplexes are "A-form" and that DNA duplexes are "B-form",

but it's important to point out that RNA duplexes have special characteristics.

They tend to be highly regular, but relative to B-form DNA

as we'll see in a minute, they often appear a little bit squashed and compact,

almost as if they were little barrels.

So some features of RNA secondary structures,

if you look at them at high resolution, are that the minor groove actually looks like the bigger groove in RNA,

and its very large and very flat.

The major groove is very narrow and quite deep.

One of the reasons that RNA duplexes look more squished together is that there's only 2.6 Angstroms between each set of stacked bases.

I also like to point out that RNA and DNA molecules don't just include the atoms inherent to the RNA and DNA:

water plays a very, very important part in their structure

and when we obtain ultra high-resolution crystal structures of RNA and DNA,

you see that water is an integral part of the structure

and often forms beautiful lattices that connect the polar regions of the molecule.

So for a minute now, let's compare RNA with B-form DNA.

As I mentioned before, B-form DNA appears more elongated

and that's because it has 3.4 Angstroms between each set of stacked base pairs.

In B-form DNA the major groove is really wide and it's somewhat deep.

The minor groove is less wide and it has about the same depth as the major groove.

And, interestingly, in DNA there are 10 base pairs per turns.

And, remember the sugars have that conformation

that gives them that long inter-phosphate distance,

thereby giving rise to a longer polymer.

RNA is quite different:

you can see that it has 11 base pairs per turn, because there is less space between the base pairs

and as I mentioned before, the major groove is very deep,

but the inter-phosphate distance across the groove is really short.

And the minor groove is quite wide and shallow.

So now we've talked about what RNA duplexes look like and what they're made of,

but an important thing to be keeping in mind is how stable they are

and how you can determine their relative level of stability.

Now, one can do this simply by knowing their sequence,

and this is a result of the work by an investigator named Doug Turner,

who figured out that RNA duplexes are not simply stabilized by the number of base pairs, or hydrogen bonds between the base pairs.

The relative stability in an RNA molecule and in an RNA duplex is dictated by the stacking between neighboring base pairs.

And he came up with a set of rules, called Turner's Rules,

that tell us that for a given set of neighbors, depending on the nearest neighbors,

you'll have a very set free energy of stabilization for that given sequence.

So for example,

here you can see that for a U-A base pair that's stacked upon an A-U base pair,

you have 1.1 kcal/mol of thermodynamic stabilization.

But, intriguingly, if you have a G-C pair that's stacked upon a C-G,

it's 3.4 kcal/mol of stabilization.

And so, if you know the sequence of your duplex, as I've shown here,

what you can do is you can actually sum up the nearest neighbor interactions

for each type of pairing and you can determine, just on the back of the envelope,

the stability of a duplex of interest.

You do have to pay a penalty for bringing two strands together to make one,

and that is something that you have to take out of the sum,

but the bottom line is that all the different computer programs that you use to calculate stabilization of an RNA,

or in the case of DNA to calculate the stability of a primer, are based on this nearest neighbor concept.

So we've just discussed the elements of RNA secondary structure

and we've also talked about what kinds of features stabilize RNA secondary structure,

so now we're going to put all of those pieces together

and describe the elements of RNA tertiary structure

and discuss a little bit how it forms as well.

So I define RNA tertiary structure as the arrangement

of helices and other structural units in three-dimensional space.

The way I like to think about it is:

it's going from here, secondary structure,

to here, the globular structure and functional structure of an RNA.

And the example I'm showing you here is a tRNA.

Very often we call the secondary structure the "RNA roadkill diagram"

because it looks like the RNA has been run over by a truck.

And, in the presence of magnesium,

which is the most important feature in stabilizing three-dimensional RNA structure,

we get these beautiful shapes.

And so I'll try to walk you through this process.

So how does RNA tertiary structure form?

Well, we've discussed the primary sequence of RNA

and I'm showing it to you here as if it were a very disordered spaghetti-like structure,

but if you were to add monovalent cations of any type, and especially monovalent cations,

you would be able to achieve the secondary structure of your RNA.

And in the secondary structure, as we've discussed,

you have your regions of double-stranded and loop character.

Now when you add divalent cations,

and in our cells those are usually magnesium ions,

then we can move from here to here,

and attain the arrangement in three-dimensional space of these elements

and we can observe tertiary structure formation.

It's worth pointing out at this point that in our cells,

the primary cations that are going to be available for RNA structure formation

are going to be potassium, as the monovalent ion, and magnesium.

So what are the building blocks for RNA structure during its formation?

Well, again, let's imagine we start out with the secondary structure, our roadkill diagram.

The first thing that's going to happen

when that molecule encounters divalent cations like magnesium is a process called coaxial stacking,

in which regions of short duplex, shown here,

actually stack on one another to form long contiguous duplexes.

In this part B here, you can see that the yellow stem stacks on the light blue stem

and the purple stem stacks on this cyan stem to form two long duplexes.

And this is usually the very first phase of the process.

At that point, then tertiary interactions form and we'll be discussing the details of some of those,

and this gives rise at the end to the globular structure.

So, because the building blocks of RNA tertiary structure are often RNA duplexes,

I'd like to review a few tertiary structures that are primarily composed of base pairing.

One of the most interesting and prominent in all structures is the pseudoknot structure.

And a pseudoknot is an interesting motif in which you have basically an RNA hairpin loop,

and the loop nucleotides form Watson-Crick base pairs with an adjacent strand.

And when this happens, amazingly, these two duplexes stack on top of each other

as in this structure of a receptor for biotin and

they form one contiguous duplex and the intervening strands snake through the major and minor grooves.

Another building block for three-dimensional shapes in RNA is called the tetraloop-receptor motif

and it was first visualized by Cate & Doudna

when they elucidated the substructure of a folding motif in a group I(1) intron.

And in this structure, another highly conserved tetraloop,

which I'm showing you here,

docks with a very conserved internal loop that's known as its receptor.

It's worth noting that very commonly in conserved RNA molecules,

many of the tetraloops will have this sequence 'GAAA'

and that's because that sequence is likely to have a partner

somewhere else in the molecule of this same sequence.

And when they come together, as shown in this crystal structure,

they dock together and they stabilize and bring together distal portions of the molecule.

Another substructure that's based on Watson-Crick pairing is the RNA kissing loop,

whereby if you have adjacent stems,

often times the loop sequences can actually form Watson-Crick base pairs with each other.

And it's amazing that this can form and that the intervening backbones permit this arrangement of the two duplexes.

And this was first visualized by Lee & Crothers, who saw that here is the loop duplex forming

and coming out of either side is the stem duplex, giving rise to an RNA shape that has about a 90 degree angle.

I'd also like to point out that many of the tertiary interactions

that stabilize RNA tertiary structure do not involve base pairing,

but involve the sugar residue,

because remember, the sugar is what makes RNA very, very special.

And again, this is largely due to the fact that the 2'-OH group

is both a hydrogen bond donor and acceptor.

And so one of the most interesting motifs that involves the 2'-OH group is called the ribose zipper.

This is a motif whereby

when sugar moieties on two RNA strands get very close together in space,

the 2'-OH groups actually interdigitate with one another

and form long networks of hydrogen bonds as shown here.

And these kinds of ribose zippers provide extra thermodynamic stabilization

for many RNA substructures that we observe.

You can think of them almost as a glue that helps to knit complex architectural forms together in RNA molecules.

Now, in RNA, we don't just have simple Watson-Crick base pairs between two nucleobases:

RNA molecules often contain three-stranded, and often four-stranded structures

whereby the nucleobases themselves form additional interactions.

This is exemplified here by the fact that an A-U base pair,

shown here, can form an interaction with a third strand nucleotide, in this case a U,

and you can see that there is good complementarity in hydrogen bonding

between the incoming third strand base and the major groove edge of this adenosine.

And we sometimes see these in long arrays, both in the major groove

and in some cases in the minor groove of RNA and these play a very important role in structure.

Today, we've talked about RNA primary structure, RNA secondary structure,

and we've talked about the nuts and bolts that put together an RNA tertiary structure,

which can get as elaborate as something like so.

So hopefully I've helped you understand that if you understand how an RNA is built,

you may be able to understand a little bit about its function.

Another thing I hope you came away from this talk with is an understanding

that RNA structures are not just the simple helix that one is used to think about,

but that they can adopt very complicated forms

and this is why we have so much functional diversity in the RNA world.

Thanks for listening!

아이가 2살 무렵 어린이집에서 형님들이 가져온 공룡인형에 울음을 터뜨렸다고 알림장에서 본게 엊그제 같은데,

'공룡에 대해 가장 많이 아는 시기' 그래프처럼 공룡지식이 나날이 높아지고 있다.

이케아 가서는 브라키오사우르스 인형은 안고 나왔었고... (+캐셔 여사님은 여아가 공룡을? 신기해 하셨지)

그리고 자연스레 나도 공룡과 관련한 장난감이나 책을 아이만큼이나 보고 있다.

아직 자연사 박물관 수준(피칠갑 정도?)의 티라노사우르스는 못 보고, 공룡인형 갖고 놀거나 만화화된 그림을 같이 보는 정도이다.

그러다 '공룡 메모리 게임'에 24 종류나 되는 공룡이 나와서 같이 이름 맞추거나, 수수께끼 내는 놀이를 같이 하고 있다.

어제는 모든 공룡 짝맞추기 놀이를 다하고 나서는

모사사우르스, 알로사우르스, 티라노사우르스, 딜로포사우르스 4마리만 '나쁜 공룡'이야 하면서 아빠가 가져가라고 한다.

그리고 나머지 애들은 모두 '예쁜 공룡'이니깐 나니가 밥줄거야하더니,

'주렁주렁' 동물원에서처럼 종이컵에 모이를 받는 척을 하더니 '예쁜 공룡'들에게 피딩을 시작했다.

도대체 24마리 중에서 왜 4마리만 "나쁜 공룡"일까?

파키케팔로사우르스는 머리에 뿔이 듬성듬성 솟아 있고,

테리지노사우르스는 발톱이 엄청 날카롭고 뾰족해보이는데, 

도대체 무슨 근거로 분류했는지 알 수가 없었다.

날카로운 이빨도 아니였고, 울긋불긋 피부색, 육식 공룡이서도 아니었다.

본인에게 물어도 봤는데, 그냥 나쁘단다.

그렇지. 그냥 나쁘면 '나쁜 공룡이지'. 니 말이 맞다.

한참을 '나쁜 공룡'과 '예쁜 공룡' 차이가 뭘까 드려다 봤더니,

본인도 모르는 로직(?)을 찾았다.

위에 '공룡 메모리 게임' 표지 보면 더 빨리 이해가 될텐데,

'나쁜 공룡' 중에 하나인 티라노사우르스의 눈이 브라키오사우르스보다는 무서워 보인다.

눈꺼풀이 더 내려오게 표현해 놓은 덕에 사나워 보이는데,

딱 4 마리 공룡의 눈만 그렇게 그려져 있었다.

날카로운 이빨/발톱/뿔, 울긋불긋 피부색, 육식 여부보다 직관적인 눈빛의 차이로

아이가 보기엔 '나쁜'과 '예쁜'을 구분한 인사이트 또는 로직이었다.

이 것은 과학적 근거가 있었네.

"스웨덴 오레브로 대학의 마트 라르손 박사는 과학전문지 '생물심리학(Biological Psychology)' 최신호에 발표한 연구논문에서 눈의 홍채(虹彩)에 있는 구멍(음와)과 선(수축구)을 분석하면 그 사람의 성격을 알 수 있다고 밝혔다.홍채의 구멍과 선들은 동공이 확대될 때 형성된다.라르손 박사는 428명의 홍채를 근접촬영한 사진을 분석하고 각자 성격에 관한 설문조사를 실시한 결과 구멍이 많은 사람들은 성격이 온화하고 따뜻하며 사람을 쉽게 신뢰하는 성격인 반면 선이 많은 사람은 신경질적이고 충동적인 성격인 것으로 나타났다고 말했다.라르손 박사는 홍채의 이러한 차이는 태아 때 홍채의 발달을 조절하는 유전자로 알려진 PAX6 신경발달유전자에 의해 형성되는 것으로 생각된다면서 홍채의 이러한 개인적 특징은 개인차를 나타내는 생물표지(biomarker)로 이용될 수도있을 것이라고 밝혔다.이 유전자가 변이되면 충동적 성격을 갖게 되고 사회성이 저하된다는 연구결과도 있다고 라르손 박사는 지적했다.이에 대해 영국 버킹엄셔 칠턴스 대학 심리학교수인 조지 필드먼 박사는 유전자에 의해 형성되는 성격적 특징을 눈의 홍채를 통해 구별할 수 있다는 것은 놀라운 일이라고 말하고 "눈은 마음의 창"이라는 금언은 유전적 근거에서 나온 것으로 보인다고 덧붙였다."

눈의 홍채에 있는 구멍(음와)이 많은 "예쁜 공룡"들처럼,

동그란 동그라미(나니가 그림 그릴 때 하는 말)가 가득한 눈빛을 가진 아이로 클수 있도록,

나부터 동그란 동그라미가 되어야하겠지 🙂

도서관에서 공룡구급대와 공룡중장비 책도 빌렸다.

트리케라톱스가 소방차도 몰고, 알로사우르스가 굴착기도 땅도 파는 내용 🤪

+ 공룡 메모리 게임은 '코리아보드게임즈'에서 만들어요!

Newy - News script 로 영어공부하기 좋음

짧은 것부터

대법원은 다음 주에 법적 문제에 대한 구두 변론을 들을 예정입니다. 

바이든 행정부는 연방 정부가 대규모 고용주를 대상으로 하는 백신 및 검사 명령을 차단하지 말 것을 대법원에 촉구하고 있습니다. 

법무부는 이 요건이 목숨을 구하고 입원 급증을 방지할 것이라고 말했습니다.

법무부는 또한 법원이 백신 명령을 차단하더라도 테스트 및 마스크 요구 사항은 그대로 유지해야 한다고 말합니다.

Biden Administration Urges Supreme Court Not To Block Vaccine Mandate

대법원은 구두 변론 들을 예정

행정부는 백신 명령 차단 금지 촉구

법무부는 사망/입원 방지

법무부는 요구사항은 유지

🧑‍⚖️👂👄

👨‍💼🧑‍⚖️🙅‍♂️💉🚫

😷💉⽣

👍😷💉

Biden Administration urges the Supreme court not to block the vaccine mandate

The Supreme court is set to hear the oral arguments on the legal challeges next week.

Biden Administration is urging the court not to block its federal vaccine and testing mandate for large emplyers.

The Department of Justice says the vaccine and testing could save many lives and prevent a surge in hospitalizations.

Also the DOJ says even if the court blocks the vaccine mandate, testing and mask requirements should remain in place.

I have experienced many special occasions throughout my life. However, one very special occasion was my graduation. All of my family and friends came to my graduation to celebrate with me. I graduated from university and received my master’s degree, so they were very happy for me. Even though it seems like yesterday, it was actually 15 years ago in the winter. Specifically, it was in the month of Feburary. I graduated from Michigan State University, which is a well-known university in Michigan. I worked very hard for my degree. So, I was happy to be able to share my graduation with my family and friends.

1. WHO 🤖
   /특별한 일 많음/ /특히 졸업/ /가족, 친구들 축하해줬음/ 
   🎓🧑‍🎓🎉
   가족, 친구들이 졸업을 축하하러 대문 앞까지 온 모습
   I have experienced many special occations through my life.
   However, one very special occation was my graduation.
   All of my family and friends came to my graduation to celebrate with me.
   
   
2. WHAT🚗
   /석사학위 받아 다들 좋아함/
   🎓🎊
   학위증을 들고 정원에 들어옴
   I graduated from university and recieved my master's digree, so they were very happy for me.
3. WHEN⏰
   /15년 전/
   ⏰
   현관의 시계가 15분 정도 임
   Even though it seems like yesterday, it was actually 15 years ago in the winter.
   Specifically, it was in the month of Feburary.
4. WHERE🗺
   /미시간에서 졸업/
   🎓🎊
   거실에 학교 사진이 있는 
   I graduated from Michigan State University, which is a well-known university in Michigan.
5. WHY🤔
   /학위 위해 열심히 했고, 가족, 친구들과 함께해서 행복/
   🎓🎊
   책장에 전공 서적과 가족, 친구들과 함께한 사진을 본 모습
   I worked very hard for my degree. 
   So, I was happy to be able to share my graduation with my family and friends.
6. +HOW🔑
   /모든 경험이 놀라움//나는 내가 자랑스러움//가족과 친구들의 지원에 감사함/
   🙏
   작은 방에 내 상장이 걸려있는 모습
   The entire occasion made me feel amazing.
   I was also proud of myself because I never gave up, even though my classes were extremely hard.
   But, I was also grateful to my family and friends for their support each and every day.
7. ++STORY🐲
   /특별한 일이 생각 남//부모님이 날 도와 주심// 학위 과정 중 희생 해주심//연단으로 부모님 부름//같이 울었음/
   /날 도와 주는 사람에게 감사하라고 가르치심//난 잊지 않을 것임/
   🙏😭👨‍👩‍👧‍👦
   큰 방에서 가족들이 엉엉 우는 모습
   One special thing that I remember from the occasion happed when I received my diploma.
   As I mentioned, my parents have always supported me.
   Throughout my time in university, my parents sacrified everything for me so that I could reach my dreams.
   So, when I got up to receive my degree, I called my parents to the stage as well.
   They cried tears of joy as we stood on the stage together holding my degree high in the air.
   My parents taught me that it is important to always thank people who have helped you.
   I will never forget that lesson.

I have experienced many special occasions throughout my life.

However, one very special occasion was my graduation.

All of my family and friends came to my graduation to celebrate with me. 

I graduated from university and received my master’s degree, so they were very happy for me. 

Even though it seems like yesterday, it was actually 15 years ago in the winter.

Specifically, it was in the month of Feburary. 

I graduated from Michigan State University, which is a well-known university in Michigan. 

I worked very hard for my degree.

So, I was happy to be able to share my graduation with my family and friends.

The entire occasion made me feel amazing.

I was also proud of myself because I never gave up, even though my classes were extremely hard.

But, I was also grateful to my family and friends for their support each and every day.

One special thing that I remember from the occasion happened when I received my diploma.

As I mentioned, my parents have always supported me.

Throughout my time in university, my parents sacrificed everything for me so that I could reach my dreams.

So, when I got up to receive my degree, I called my parents to the stage as well.

They cried tears of joy as we stood on the stage together holding my degree high in the air.

My parents taught me that it is important to always thank people who have helped you.

I will never forget that lesson.